Profile
Dr Ines Díaz del Olmo
Profile
I completed a BSc (Hons) in Health Biology at the University of Alcalá (Spain) in 2015 and an MRes in Microbiology, specialising in human pathogens, at the Autonomous University of Madrid (Spain) in 2016. In 2021, I obtained my PhD in Immunology from the University of Manchester, where I studied inflammatory processes in innate immune cells. I then joined Imperial College London as a Postdoctoral Research Associate, investigating mechanisms of immune evasion by pathogens. In 2024, I moved to the University of Oxford to continue this work at the Sir William Dunn School of Pathology, and in 2025 I joined Lincoln College as a BTG Junior Research Fellow in Biomedical Sciences.
- Research
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My research is driven by a strong interest in understanding how the immune system responds to danger signals in the context of inflammatory and infectious diseases. My current research investigates how the human pathogen Salmonella Typhimurium evades immune detection and control. My work examines how innate immune cells, particularly macrophages, respond to the mechanisms by which this pathogen hijacks them, using them as niches for survival, replication, and dissemination.
- Select publications
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‘Bacterial effectors mediate kinase reprogramming through a series of evolutionary conserved amino acids that mimic eukaryotic motifs’ EMBO Reports, 2025, Volume 26, 3529–3553. DOI: 10.1038/s44319-025-00472-y
‘Speaking the host language: how Salmonella effector proteins manipulate the host’ Microbiology, 2023, 169(6):001342. DOI: 10.1099/mic.0.001342.
‘Internalization of the Membrane Attack Complex Triggers NLRP3 Inflammasome Activation and IL-1β Secretion in Human Macrophages’. Frontiers in Immunology, 2021, Volume 12. DOI: 10.3389/fimmu.2021.720655
‘Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro’. Frontiers in Immunology, 2020, Volume 11. DOI: 10.3389/fimmu.2020.565924
Position
- BTG Junior Research Fellow in Biomedical Sciences