Front Quad of Lincoln College, the walls covered in bright green ivy

Dr Andrii Gorelik

Jones and Anson Junior Research Fellow in the Biosciences
Sir Henry Wellcome Postdoctoral Fellow

Profile

I received my undergraduate degree in industrial biotechnology in 2014 from the Kyiv Polytechnic Institute (Ukraine). I then moved to the University of Dundee (UK) to complete a Wellcome Trust-funded PhD in 2018, establishing novel methods for functional dissection of site-specific protein O-GlcNAcylation. After completing my PhD, I undertook postdoctoral research at the Francis Crick Institute and Imperial College London on protein N-myristoylation in MYC-driven cancers. Since 2022, I have been the Sir Henry Wellcome Fellow at the Sir William Dunn School of Pathology, working on ADP-ribosylation in cancer, and the Jones and Anson Junior Research Fellow in Biosciences at Lincoln.

Research

My research interests are in molecular mechanisms of post-translational protein modifications in health and disease with a particular focus on cancer.

Select publications

'N-myristoyltransferase inhibition is synthetic lethal in MYC-deregulated cancers', 2021, doi: 10.1101/2021.03.20.436222

'Tools for functional dissection of site-specific O-GlcNAcylation', 2020, pp 98-109. doi: 10.1039/d0cb00052c

'Genetic recoding to dissect the roles of site-specific protein O-GlcNAcylation', PMID: 31695185, 2019 Nov;26(11):1071-1077. doi: 10.1038/s41594-019-0325-8